😃 Brief Bio

Hi! Welcome to the personal page of Kaiqi. I was born in Foshan, Guangdong, China in 1996. I obtained PhD degree from Department of Pharmacology and Pharmacy, The University of Hong Kong in 2023, supervised by Prof. Weiping Wang.

My research interest includes photochemistry, ocular drug delivery, molecular self-assembly, optical devices, etc.

I will join Brigham and Women’s Hospital, Harvard Medical School as postdoctoral fellow in Feb 2024. I will work on nucleic acid delivery there with Prof. Jinjun Shi.

If you are seeking any form of academic cooperation with me, please feel free to contact me at longkq@hku.hk.

For more details, please refer to my CV. (last updated: Dec 2, 2023)

📻 News

• 2023.12:   Kaiqi finished his PhD study in HKU.
• 2023.11:   Kaiqi gave an oral talk on 4th International Conference on PhotoPharmacology (Hong Kong, China).
• 2023.06:   Kaiqi gave an oral talk on 13th International Nanomedicine Conference (Sydney, Australia).
• 2022.11:   Kaiqi was awarded Dissertation Year Fellowship by HKU.

📝 Publications

15- Near-infrared Light-Triggered Prodrug Photolysis by One-step Energy Transfer

Kaiqi Long, Wen Lv, Zihan Wang, Yaming Zhang, Kang Chen, Ni Fan, Feiyang Li, Yichi Zhang, Weiping Wang*   Nature Communications, 2023, Accepted

14- Red light-triggered anti-angiogenic and photodynamic combination therapy of age-related macular degeneration

Shuting Xu¹, Kaixuan Cui¹, Kaiqi Long, Jia Li, Ni Fan, Wai-Ching Lam, Xiaoling Liang, Weiping Wang*   Advanced Science, 2023, 2301985  (Highlighted on cover)

13- Facile Preparation and Photoactivation of Prodrug-dye Nanoassemblies Yichi Zhang, Kaiqi Long, Weiping Wang*   Journal of Visualized Experiments, 2023, e64677.

12- Carrier-free nanodrugs for stemness inhibition-enhanced photodynamic therapy Yuwei Liu, Kaiqi Long, Tianyi Wang, Weirong Kang, Weiping Wang*   Aggregate, 2023, e284. (Highlighted on cover)

11- Optochemical control of immune checkpoint blockade via light-triggered PD-L1 dimerization Yuwei Liu, Kaiqi Long, Weirong Kang, Tianyi Wang, Weiping Wang*   Advanced NanoBiomed Research, 2022, 2, 6 2200017. (Highlighted on cover)

10- H2S-responsive Small-Molecule Nanocarrier for Drug Delivery to Colorectal Tumor

Kaiqi Long, Yang Yang, Zhanfeng Du, Weirong Kang, Wen Lv, Yafei Li, Yusheng Xie, Hongyan Sung, Changyou Zhan, Weiping Wang*   Advanced Therapeutics, 2022, 2200044  (Highlighted on cover)

9- Photoresponsive Prodrug-dye Nanoassembly for in-situ Monitorable Cancer Therapy

Kaiqi Long¹, Yifan Wang¹ Wen Lv, Yang Yang, Shuting Xu, Changyou Zhan, Weiping Wang*   Bioengineering & Translational Medicine, 2022, 7, 3, e10311

8- Optochemical Control of mTOR Signaling and mTOR-dependent Autophagy Tianyi Wang, Kaiqi Long, Yang Zhou, Xiaoding Jiang, Jinzhao Liu, John H.C. Fong, Alan S.L. Wong, Wai-Lung Ng, Weiping Wang*   ACS Pharmacology & Translational Science, 2022, 5, 3, 149–155

7- NIR light-triggered quantitative pulsed drug release

Yang Yang¹, Kaiqi Long¹, Yiqun Wang¹, Lei Li, Jiayue Shi, Jican Liu, Lingxi Kong, Lin Yu, Jiandong Ding, Zhili Huang*, Weiping Wang*，Changyou Zhan*   Advanced Healthcare Materials, 2022, 11, 8, 2102362

6- One-photon Red Light-triggered Disassembly of Small-molecule Nanoparticles for Drug Delivery

Kaiqi Long¹, Han Han¹, Weirong Kang, Wen Lv, Lang Wang, Yufeng Wang, Liang Ge*, Weiping Wang*   Journal of Nanobiotechnology, 2021, 19, 357

5- Photoenhanced cytosolic protein delivery based on a photocleavable group-modified dendrimer Yafei Li¹, Yang Zhou¹, Kaiqi Long, Yaming Zhang, Tianyi Wang, Weiping Wang*   Nanoscale, 2021, 13, 17784-17792 (Highlighted on cover)

4- Green light-triggered intraocular drug release for intravenous chemotherapy of retinoblastoma

Kaiqi Long¹, Yang Yang¹, Wen Lv, Kuan Jiang, Yafei Li, Amy Cheuk Yin Lo, Wai Ching Lam, Changyou Zhan*, Weiping Wang*   Advanced Science, 2021, 8, 20, 2101754 (Highlighted on cover) (High downloaded paper in 2022)

3- A Red Light-Triggered Drug Release System Based on One-Photon Upconversion-Like Photolysis

Wen Lv, Kaiqi Long, Yang Yang, Sijie Chen, Changyou Zhan and Weiping Wang*   Advanced Healthcare Materials, 2020, 9, 2001118

2- Self-assembly of trigonal building blocks into nanostructures: molecular design and biomedical applications

Kaiqi Long, Yuwei Liu, Yafei Li and Weiping Wang*   Journal of Materials Chemistry B, 2020, 8, 6739-6752 (invited review)

1- A Soluplus/Poloxamer 407-based self-nanoemulsifying drug delivery system for the weakly basic drug carvedilol to improve its bioavailability Han Han¹, Yun Li¹, Zhen Peng, Kaiqi Long, Chunli Zheng, Weiping Wang*, Thomas J. Webster*, Liang Ge*   Nanomedicine: Nanotechnology, Biology and Medicine, 2020, 27, 102199

🏅 Awards

• 2022.11   Dissertation Year Fellowship, The University of Hong Kong
• 2022.03   Gold Medal, 2022 Inventions Geneva Evaluation Days (Project: Light-responsive Ocular Drug Delivery)
• 2018-2022   Hong Kong PhD Fellowship Scheme
• 2017.09   First-class Scholarship, SYSU
• 2016.09   Enterprise Scholarship of Amitabha
• 2016.09   First-class Scholarship, SYSU
• 2015.09   China National Scholarship
• 2015.09   First-class Scholarship, SYSU
• 2014.02   Second Price, The 27th Chinese Chemistry Olympiad (CChO)

📖 Experiences

• 2024.02 - present, Lorem ipsum dolor sit amet, consectetur adipiscing elit. Vivamus ornare aliquet ipsum, ac tempus justo dapibus sit amet.
• 2018.09 - 2023.11, Lorem ipsum dolor sit amet, consectetur adipiscing elit. Vivamus ornare aliquet ipsum, ac tempus justo dapibus sit amet.
• 2014.09 - 2018.08, Lorem ipsum dolor sit amet, consectetur adipiscing elit. Vivamus ornare aliquet ipsum, ac tempus justo dapibus sit amet.

💬 Conferences

• 2023.11, Long-wavelength Light-triggered Drug Delivery by Upconversion-like Photolysis, 4th International Conference on PhotoPharmacology, Hong Kong, China (Oral Presentation)
• 2023.06, Long-wavelength Light-triggered Drug Delivery by Upconversion-like Photolysis, 13th International NanoMedicine Conference, Sydney, Autralia (Oral Presentation)
• 2021.12, Green-light-triggered Intravenous Chemotherapy of Retinoblastoma, Postgraduate Symposium, The University of Hong Kong, Hong Kong, China (Poster Presentation)
• 2021.12, One-photon Red Light-triggered Disassembly of Small-molecule Nanoparticles for Drug Delivery, 3rd International Conference on PhotoPharmacology, Virtual Conference (Oral Presentation)
• 2019.05, H2S-responsive Nanocarrier for Drug Delivery, 10th International Conference on Materials for Advanced Technologies (ICMAT 2019), Singapore (Oral Presentation)

📜 Patents

• Weiping Wang, Kaiqi Long, NIR Light-triggered Photolysis by One-step Energy Transfer, US Provisional Patent (No. 63/506,991, 2023)
• Weiping Wang, Kaiqi Long, A Controlled Drug Release System of Photoresponsive Nanocarriers, Methods of Making and Using thereof, PCT Patent (No. PCT/CN2021/081262, 2021)
• Weiping Wang, Tianyi Wang, Kaiqi Long, Compositions and Methods of Optochemical Control of mTOR Signaling and mTOR-dependent Autophagy, US Patent (No. 17/850,720, 2022)
• Weiping Wang, Kaiqi Long, Shuting Xu, Photoactivatable Prodrug Nanoparticles for Combined Anti-angiogenesis and Photodynamic Therapy, PCT Patent (No. PCT/CN2022/107621, 2022)
• Weiping Wang, Yuwei Liu, Kaiqi Long, Photoresponsive Prodrugs for Targeted Immunotherapy, US Provisional Patent (No. 63/203,87, 2021)
• Weiping Wang, Kaiqi Long,Yifan Wang, Photocleavable Prodrug-based Nanomedicine for in-situ Monitorable Cancer Therapy, US Provisional Patent (No. 63/262,789, 2021)